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The present review aims to assess the blood donation safety by people suffered from diabetes, hypertension, malaria and cancer. Diabetes, hypertension, malaria and cancer have become common health problems in human society. Cases of blood transfusion-transmitted malaria, hypertension, cancer and the safety of blood donation by diabetic people have been described around the world and highlighted in some studies. Diabetes is generally associated with complications and people with diabetes usually take different medications and may already have anaemia secondary to renal impairment, B12 deficiency. As for the recipient safety, a blood from a person with hyperglycaemia but otherwise healthy i.e. satisfy blood donation safety standards (no record of HIV, Hepatitis B or C) would be quite safe to receive as the extra glucose would simply be regulated and utilised by the recipient's body. Hypoglycemia is as bad as hyperglycemia and could be fatal and hence, generally, it is not desired that diabetics give blood donations. Diabetic patients taking bovine or porcine insulin may develop antibodies and it is not recommended that the antibody contaminated blood to be given to any other person. A person with hypertension can donate blood, as long as the blood pressure is normal at the time of blood donation and there’s no fluctuation. Malaria is also readily transmitted by blood transfusion through donations collected from asymptomatic, parasitaemic donors. The parasite is released into the bloodstream during its lifecycle and will, therefore, be present in blood donated by infected individuals. The presence of total anti-Plasmodium spp. antibodies in the bloodstream of individuals many years after exposure, with no history of malaria in the meantime, is important to highlight. Regarding donors with cancer blood donations should not be taken from people with recently active malignancies, except in the case of basal cell carcinoma or cervical carcinoma in situ.
Singh G, Sehgal R. Transfusion-transmitted parasitic infections. Asian J Transfus Sci. 2010;4:73–7.
Candolfi E. Transfusion-transmitted malaria, preventive measures. Transfus Clin Biol. 2005;12:107–13.
World Health Organization. Global Report on Diabetes. World Health Organization; 2016.
World Health Organization. Blood donor selection: guidelines on assessing donor suitability for blood donation.World Health Organization, Geneva; 2012.
UK Blood Transfusion Services’ Forum 2005. Recommendations for changes to acceptance criteria for UK whole blood and component donors, produced by a project group consulting clinical experts.
Mayo Foundation for Medical Education and Research.
American Diabetes Association;
[Cited 2016 Sep 19]; [about 1.5 screens]. Available:http://www.stopdiabetes.com/get-the-facts/myths-and-facts.html
Routi Elizabeth, Ommen S, Bernd Schröppel, Jin-Yon Kim, Gabrielle Gaspard, Enver Akalin, Graciella de Boccardo, Vinita Sehgal, Michael Lipkowitz, Barbara Murphy. Use of ambulatory blood pressure monitoring in potential living kidney donors. Ommen, Mount Sinai Medical Center, Division of Nephrology; 2007.
Hong Lin, Shaowen Zhu, Shengjiang Zhu, Lei Shao, Nan Zhu, Chengyin Huang Jun Sun. Selective malaria antibody screening among eligible blood donors in Jiangsu, China. Rev. Inst. Med. trop. S. Paulo 2017;59.
Nguyen ML, Goff T, Gibble J, Steele WR, Leiby DA. Analyzing actual risk in malaria-deferred donors through selective serologic testing. Transfusion. 2013;53: 1736-43.
Dubey A, Elhence P, Ghoshal U, Verma A. Seroprevalence of malaria in blood donors and multi-transfused patients in Northern India: relevance to prevention of transfusion-transmissible malaria. Asian J Transfus Sci. 2012;6:174-8.
Daniela Portugal-Calisto, Ana Raquel Ferreira, Marcelo Sousa Silva and Rosa Teodósio. Post-exposure serological responses to malaria parasites in potential blood donors. Malaria Journal. 2016;15: 548.
Bankole Henry Oladeinde, Richard Omoregie, Eguagie Osareniro Osakue, Tola Ohiengbomwan Onaiwu. Asymp-tomatic Malaria among Blood Donors in Benin City Nigeria. Iran J Parasitol. 2014; 9(3):415–422.
Dubey A, Elhence P, Ghoshal U, Verma A. Seroprevalence of malaria in blood donors and multi-transfused patients in Northern India: Relevance to prevention of transfusion-transmissible malaria. Asian J Transfus Sci. 2012;6:174-8.
Daniela Portugal-Calisto, Ana Raquel Ferreira, Marcelo Sousa Silva, Rosa Teodósio. Post-exposure serological responses to malaria parasites in potential blood donors. Malaria Journal. 2016;15: 548.
Bankole Henry Oladeinde, Richard Omoregie, Eguagie Osareniro Osakue, and Tola Ohiengbomwan Onaiwu. Asymptomatic malaria among blood donors in Benin City Nigeria. Iran J Parasitol. 2014;9(3):415–422.
World Health Organization. Blood Donor Selection: Guidelines on Assessing Donor Suitability for Blood Donation. WHO; 2012. Available:www.who.int