Effect of Antiasthma Medication on Blood Eosinophil Count and Serum Immunoglobulin E Levels: A Randomized Controlled Study

Main Article Content

Wasim A. Wani
Sheeraz A. Dar
Khalid M. Kawosa
Mudasir Nazir
Ikhlas Ahmad
Asif Ahmed


Background: Asthma is a chronic inflammatory condition of lung airways resulting in episodic airflow obstruction.

Aims: The main objective of this study is to find the effect of antiasthma medication on serum IgE levels and blood eosinophil count.

Study Design: This randomized controlled trial study was performed in children aged 6-15 years of age, with clinically stable and moderate persistent asthma.

Results: The findings of this study indicate both group (Budesonide/formoterol group and budesonide group) patients experienced a significant decrease in serum IgE levels and blood eosinophil counts over the study period. However, the difference in two groups was not statistically significant.

Conclusions: Inhaled steroids are effective in controlling systemic inflammation in asthma as evidenced by a decrease in IgE levels and eosinophil counts. However addition of LABA doesn’t have any additive effect.

Asthma, budesonide, eosinophil, IgE levels, inhaled steroids, LABA

Article Details

How to Cite
Wani, W. A., A. Dar, S., Kawosa, K. M., Nazir, M., Ahmad, I., & Ahmed, A. (2020). Effect of Antiasthma Medication on Blood Eosinophil Count and Serum Immunoglobulin E Levels: A Randomized Controlled Study. Journal of Advances in Medicine and Medical Research, 32(6), 33-39. https://doi.org/10.9734/jammr/2020/v32i630430
Original Research Article


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