Anesthesia for Urgent Surgery in a Patient with Angioneurotic Oedema: A Case Report

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Said Khallikane
Aziz Benakrout
Hanane Delsa
Mohamed Moutaoukil
Khalil Abou Elalaa
Samir Siah
Hicham Balkhi
Abdelouahed Baite


Hereditary angioneurotic oedema is an autosomal dominant disease associated with serum deficiency of functional C1-inhibitor. It is characterized by periodic swelling of subcutaneous tissues, abdominal viscera and upper airways. Lethal acute episodes of oedema can occur during anaesthesia and surgery. It is essential to prepare such patients before surgery. This article describes a case and the various preventive measures used to avoid acute episodes during anaesthesia for urgent surgery for mesenteric ischemia. In emergency situations where C1 inhibitor concentrate is not available, fresh frozen plasma (FFP) can be used as an alternative, as it also contains C1 inhibitor, corticosteroids, antihistamines, and epinephrine can be useful adjuncts but typically are not efficacious in aborting acute attacks. Prophylactic management involves long-term use of attenuated androgens or antifibrinolytic agents (Tranexamic acid).Their various indications are discussed.

Angioneurotic oedema, c1-inhibitor deficiency, prevention, complication.

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How to Cite
Khallikane, S., Benakrout, A., Delsa, H., Moutaoukil, M., Elalaa, K. A., Siah, S., Balkhi, H., & Baite, A. (2020). Anesthesia for Urgent Surgery in a Patient with Angioneurotic Oedema: A Case Report. Journal of Advances in Medicine and Medical Research, 32(19), 20-26.
Case Study


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