Platelet Indices in Uterine Leiomyoma Compared with other Major Gynecological Diseases
Journal of Advances in Medicine and Medical Research,
Aims: The aim of this study was to determine whether platelet indices are of value when diagnosing uterine leiomyomas.
Study Design: Prospective study.
Place and Duration of Study: Elena Doamna Obstetrics and Gynecology University Hospital, Iasi, Romania, between January 2017 and December 2017.
Methodology: In this study 98 patients were selected from 140 consecutive screened patients and operated upon; 53 of the operated-on patients had uterine leiomyoma (Group 1) and 45 had severe non-leiomyoma gynecological disease (Group 2). Complete blood count, just before the intervention was studied.
Results: The RDW-CV, PLT and PCT values were significantly higher (P = .017, P = .05, P = .001, respectively) in leiomyoma patients, whereas WBC, RBC, MPV, PDW, P-LCR, NLR, PLR were not significantly different between the 2 groups. The inflammatory indices WBC, NLR and PLR were not significantly higher in leiomyoma patients compared with non-leiomyoma patients, despite the fact that leiomyoma also has an inflammatory cause. Although leiomyomas were accompanied by acute or chronic blood loss, only RDW-CV was significantly higher (P = .017) in leiomyoma patients, whereas HCT and RBC values were not significantly different between the 2 groups.
Conclusion: The RDW-CV, PLT and PCT values were significantly higher in leiomyoma patients, whereas WBC, RBC, MPV, PDW, P-LCR, NLR, PLR were not significantly different. Still, the specificity of RDW-CV, PLT and PCT was not high enough to allow using them as diagnostic tools for leiomyoma.
- Uterine leiomyoma
- platelet indices
- white blood cells count
- red blood cells count
How to Cite
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