Evaluation of Photobiomodulation while Preventing Pressure Injuries in COVID-19 Patients: A Randomised, Controlled, Double-Blind, Clinical Protocol

Ione Liz Paiotti

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil and Nursing directorate of the Municipal Hospital of Parelheiros, São Paulo, Brazil.

Elizabeth Akemi Nishio

Coordination of the Corporate Nursing Center of the Paulista Association for the Development of Medicine, São Paulo, Brazil.

Cristiane Aparecida Betta

Technical Nursing Advisory of the Paulista Association for the Development of Medicine, São Paulo, Brazil.

Luciane Luz e Silva

Nursing Management of the Pirajussara General Hospital, São Paulo, Brazil.

Márcia Cardoso Romano

Clinical Nursing of the Prof. Dr. Waldemar de Carvalho Pinto Filho General Hospital, São Paulo, Brazil.

Lara Jansiski Motta

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil.

Sandra Kalil Bussadori

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil and Postgraduate Program in Reabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil.

Cinthya Cosme Gutierrez Duran

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil.

Raquel Agnelli Mesquita-Ferrari

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil and Postgraduate Program in Reabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil.

Anna Carolina Ratto Tempestini Horliana

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil.

Kristianne Porta Santos Fernandes *

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil.

*Author to whom correspondence should be addressed.


Abstract

Due to the high incidence, pressure injuries (PIs) are considered a serious public health problem and a negative indicator of the quality of nursing care. The aim of the present study is to investigate the preventive effects of photobiomodulation (PBM) applied to areas most susceptible to the development of PIs in patients hospitalised with COVID-19. This paper describes the protocol for a randomised, controlled, double-blind, clinical trial involving hospitalised participants at high or moderate risk of developing PIs. The participants were randomised into two groups: a control group (n = 70) submitted to the standard institutional procedures for PI prevention and a PBM group (n = 70) submitted to the same procedures as the control group, along with PBM applied once per day for 10 minutes to each of the three most commonly affected regions (sacral and bilateral calcaneal areas). PBM was administered using a 264-LED panel consisting of 132 LEDs at a wavelength of 660 nm and 132 at 850 nm. The incidence of PI was investigated every 48 hours after hospital admission for a period of one month. Statistical analysis will be performed considering α = 0.05.

Keywords: Pressure ulcer, photobiomodulation, low-level laser therapy, primary prevention, bedsores, primordial prevention, sepsis, gangrene


How to Cite

Paiotti, Ione Liz, Elizabeth Akemi Nishio, Cristiane Aparecida Betta, Luciane Luz e Silva, Márcia Cardoso Romano, Lara Jansiski Motta, Sandra Kalil Bussadori, Cinthya Cosme Gutierrez Duran, Raquel Agnelli Mesquita-Ferrari, Anna Carolina Ratto Tempestini Horliana, and Kristianne Porta Santos Fernandes. 2025. “Evaluation of Photobiomodulation While Preventing Pressure Injuries in COVID-19 Patients: A Randomised, Controlled, Double-Blind, Clinical Protocol”. Journal of Advances in Medicine and Medical Research 37 (3):302-9. https://doi.org/10.9734/jammr/2025/v37i35766.