Open Access Case Report

Aplastic Anemia during Pregnancy with Complete Remission: Case Report and Review of the Literature

Regaieg Haifa, Achour Bechir, Bouslema Emna, Achour Amel Jenayah, Ben Sayed Nesrine, Bouatay Bouzouita Amina, Ben Youssef Yosra, Khelif Abderrahim

Journal of Advances in Medicine and Medical Research, Page 1-4
DOI: 10.9734/BJMMR/2017/29613

The association of aplastic anemia (AA) and pregnancy is exceptional and there are no clear guidelines for its management, It could be life threatening for both mother and child and a challenge to the hematologist as well as the obstetrician. Sometimes it improves spontaneously after delivery. We report a case of pregnant woman in whom severe AA was diagnosed, managed during pregnancy with supportive therapy leading to normal delivery of a full term healthy foetus, with good outcome after a follow up of three years.

Open Access Short Communication

Making of Primary Impression Made Easy for Severely Resorbed Mandibular Ridge – A Clinical Case Report

Manish Sen Kinra, Divia Chugh, Inderjit Murugendrappa Gowdar, Shoaib Khan, Mohammed Zaheer Kola, Bavika Sachdeva

Journal of Advances in Medicine and Medical Research, Page 1-8
DOI: 10.9734/BJMMR/2017/28923

This article describes the making of a functional primary impression for severely resorbed mandibular ridge type IV. In this technique metal wire of 1.5 mm diameter was adapted on the ridge of a mandibular arch from one retromolar pad to another retromolar pad. On the metal wire addition silicone putty was adapted and phonetics was used for making an initial primary functional impression. The prepared initial primary functional impression was under extended. Thus correction was done by adding putty addition silicone impression material. Later wash impression was made using addition silicone light-bodied impression material. The prepared impression was accurate in term of reproduction of details, and in term of extensions it was a functional impression. An impression was not deformed by the manipulations done by the dentist or by using oversized or undersized stock trays.

Open Access Minireview Article

The Effect of Denitrification in the Human Dental Biofilm on Oral Tissues

Luay Thanoon Younis, Mohamed Ibrahim Abu Hassan, Tara Bai Taiyeb Ali

Journal of Advances in Medicine and Medical Research, Page 1-5
DOI: 10.9734/BJMMR/2017/29816

Global oral health surveys reveal that periodontal disease and dental caries affect human populations throughout the world. Denitrification plays both positive and negative roles in these disease processes by producing by-products that alter the oral environment, change the oral ecological balance, and the oral tissue immune response. Nitrate reduction may have a detrimental effect on the tooth supporting structures if the by-products of reduction are not neutralized. However, the nitrogen oxide by-products are beneficial in reducing dental caries. In this paper, we review the process of denitrification and its effect on the oral tissues.

Open Access Original Research Article

Procalcitonin as a Predictor for Severity and Etiology of Community Acquired Pneumonia (CAP)

Ahmad Abdelsadek, Osama Abuel Naga, Manal A. Shams Eldin Eltelbany, Azza Hamdy

Journal of Advances in Medicine and Medical Research, Page 1-8
DOI: 10.9734/BJMMR/2017/29686

Aim of the Work: To study the role of procalcitonin as a predictor for severity and etiology of community   acquired pneumonia (CAP).

Subjects and Methods: This study was carried out on 60 hospitalized adult patients with CAP classified into; group I included 30 mild and moderate (15 atypical and 15 typical CAP) and group II included 30 patients with  severe CAP (15 atypical and 15 with typical CAP). All subjects were submitted to full history, full clinical examination, chest X-ray (postero-anterior and lateral views) and CT chest in some cases, routine laboratory investigations (complete blood count, liver function tests, kidney function tests and fasting blood sugar), arterial blood gases, microbiological workup, H1N1 and Corona viruses were performed for all patients according to policy of ministry of health, Kingdom of Saudi Arabia. Procalcitonin (PCT) measured within 24 hours of admission.

Results: The study revealed significant higher level of PCT levels in patients with severe CAP- regardless atypical or atypical-with no significant difference between severe atypical and typical CAP. Significant higher PCT levels in patients with severe CAP than patients with mild and moderate CAP. Significant higher level of PCT levels in patients with mild and moderate typical CAP than mild and moderate atypical CAP. The X-Ray and CT findings in relation to typical and atypical CAP revealed that the highest PCT level was recorded in consolidation pattern CAP followed by peri-bronchial pattern then ground glass pattern while the lowest level was recorded in random nodular pattern. Positive correlation between Severity of pneumonia according to pneumonia severity index and PCT level.

Conclusions: PCT measurement may provide an important predictor for severity of CAP, while play a little role as a predictor of etiology.

Open Access Original Research Article

A Priliminary Study on In-hospital Outcome of Stroke in a Tertiary Centre of South Bengal, India

Sumit Chatterjee, Paramita Bhattacharya, Manas Ghosh, Amitava Acharyya, Kaushik Ghosh

Journal of Advances in Medicine and Medical Research, Page 1-10
DOI: 10.9734/BJMMR/2017/30300

This single centre descriptive observational design study was undertaken in a tertiary referral centre of South Bengal, India in an attempt to assess the outcome of stroke according to various risk factors and Glasgow coma scale at the time of admission. A better outcome was considered as Glasgow outcome scale score of 4 and 5 while poor outcome was considered as Glasgow outcome scale score of 3 or less.

Open Access Original Research Article

Experience with Combined Injectable Contraceptive (Norigynon) in Port Harcourt

Ojule John Dimkpa, Oranu Emmanuel Okwudili

Journal of Advances in Medicine and Medical Research, Page 1-6
DOI: 10.9734/BJMMR/2017/29727

Aims: To evaluate the use, acceptability, effectiveness and side effects of combination injectable contraceptive (CIC) in Port Harcourt, Niger Delta Region of Nigeria.

Study Design: Descriptive retrospective analysis.

Place and Duration of Study: Family planning clinic, University of Port Harcourt Teaching Hospital, Port Harcourt Nigeria, between 1st January 2010  and 31st December, 2013.

Methodology: The case notes of all new clients who accepted combined injectable contraceptive (Norigynon) were retrieved from the records section of the clinic and studied.

Data, including socio-demographic characteristics, adverse effects and reasons for contraception were extracted and analysed using SPSS for windows 19.0 version and results expressed in percentages and presented in tables.

Results: Of the 1260 new acceptors of modern contraceptive methods in UPTH, 21 clients chose the combined injectable contraceptive (Norigynon) giving an acceptance rate of 1.67%. All (100%) of the acceptors used it for child spacing. Five (23.81%) reported side effects which were oligomenorrhea, (1, 14.76%), intermenstrual bleeding, (2,9.52%) and secondary amenorrhea, (2, 9.52%). Twelve (54.14%) were lost to follow up. There was no pregnancy reported among the users, giving a Pearl index of zero.

Conclusion: Combined injectable contraceptive is a very effective and safe method of contraception but with surprisingly very low uptake and continuation rates in Port Harcourt, Southern Nigeria.

Open Access Original Research Article

Seroprevalence of Hepatitis B and C Infections among Adult Males in Beit al-Faqih District, Al-Hodeidah Governorate, Republic of Yemen

Ahmed M. O. Al-Kadassy, Foud A. Balkam, Salem Bashanfer

Journal of Advances in Medicine and Medical Research, Page 1-6
DOI: 10.9734/BJMMR/2017/27623

Background: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are major causes of liver disease worldwide and can cause acute and chronic hepatitis which may lead to hepatic cirrhosis or even cancer, thus creating a significant burden to healthcare systems due to the high morbidity/mortality and costs of treatment.

Aim: To determine the seroprevalence of hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV) among adult males in Beit al-Faqih districts, Hodeida, Yemen.

Study Design: A cross sectional study.

Place and Duration of Study: Samples were collected from 4 areas in Beit al-Faqih district, Hodeidah city, Yemen, during the period November 2012 - December 2015.

Methodology: Blood samples were collected from 1289 adult males, screening test of HBV surface antigen and antibodies against HCV were performed through enzyme linked immunosorbent Assay.

Results: HBV and HCV were detected in 208 (16.1%) subject. The prevalence rate of HBV and HCV were found in 187 (14.5%) and 21(1.6%), respectively.

Conclusion: This study demonstrates that the prevalence of HBV and HCV infections is high among adult males in Beit al-Faqih District, Al-Hodeidah Governorate, Republic of Yemen.

Open Access Original Research Article

Development of a Potentially Individualized Algorithm to Detect Heart Failure Events through Home Telemonitoring

Kiswendsida Sawadogo, Jérôme Ambroise, Steven Vercauteren, Michel Vanhalewyn, Marc Castadot, Jacques Col, Annie Robert

Journal of Advances in Medicine and Medical Research, Page 1-14
DOI: 10.9734/BJMMR/2017/29098

Aims: Home telemonitoring represents a promising approach to reduce heart failure (HF) patients’ hospital readmissions. The aim of the study was, in a first step, to identify the monitored parameters’ characteristics that are predictive of HF events. In a second step, it was to build a prediction score by combining both the identified characteristics and the patients’ clinical prognosis.

Methods: Patients completed 6-month blind daily body weight, blood pressure and pulse measurements. A cardiac composite endpoint (CCE) of death, hospitalization or urgent visit was considered. A series of signal-derived statistics (SDS) were computed on 3, 5 and 7 days’ time windows. A signal score for CCE prediction was built by including SDS in a first logistic model using a subset of signal set (training) and its accuracy was assessed in another subset (testing). A clinical score was computed using the Meta-Analysis Global Group in Chronic Heart Failure formula. Both scores were combined using a second logistic model. We compared the three scores using ROC curves.

Results: Monitoring was completed by 146 patients and 96 CCE occurred in 61 patients. The first logistic model resulted in a signal score which combined 7 SDS including body weight’s variability on 3 consecutive days, body weight’s increase on 3 and 7 consecutive days, pulse’s variability on 3 and 7 consecutive days, diastolic  blood pressure’s mean on 3 consecutive days, differential pressure’s variability on 3 consecutive days. The signal score had ability in predicting CCE occurrence (training set: AUC= 0.796, P < .001; testing set: AUC=0.830, P < .001). The second logistic model resulted in a combined score that improved CCE prediction (training set: AUC= 0.830, P < .001; testing set: AUC= 0.891, P < .001) with 92% sensitivity and 77% specificity.

Conclusions: Signal data and clinical data provide additive information to risk prediction.

Open Access Original Research Article

Female Sexual Dysfunction among Kosovo Women

Hajrullah Fejza, Ilir Tolaj, Behrije Vishi, Albina Fejza, Liridona Jemini, Minire Alilaj

Journal of Advances in Medicine and Medical Research, Page 1-6
DOI: 10.9734/BJMMR/2017/29615

Aim: The purpose of this study was to analyze female sexual dysfunction and potential risk factors influencing the sexual life in Kosovo’s women population. 

Study Design: Cross-sectional analysis

Place and Duration of Study: This study was conducted through an online survey in Kosovo, between May-September 2015.

Methods: A self‑administered structured questionnaire, A Brief Sexual Symptom Checklist for Women, (BSSC) was administered to assess overall satisfaction (prevalence), desire, genital sensation, lubrication, orgasm and pain. The respondent rate was 87.5% (350/400).

Results: The level of sexual dissatisfaction was 36.9%. Little or no interest in sex was reported in 32% of women, an orgasmic problem in 20%, genital sensation problem in 16.7%, a lubrication problem in 12.7% and pain during sex in 16.0%. 76.8% of women would like to talk about these problems with their doctor.  Age and smoking history are the potential risk factors.

Conclusion: The level of sexually dissatisfied women in Kosovo is quite high but similar to other studies within the field.  The willing to discuss with a doctor was reported by 2/3 of respondents. The level of satisfaction is in correlation with age. The second most important risk factor is smoking. 

Open Access Original Research Article

Health Workers’ Practice of Preventing Mother-to-child Transmission of HIV in Benin City, Edo State, Nigeria

T. Ashipa, A. N. Ofili

Journal of Advances in Medicine and Medical Research, Page 1-9
DOI: 10.9734/BJMMR/2017/29257

Introduction: Health workers have an important role to play in preventing mother-to-child transmission of HIV. This study assessed health workers’ practice of preventing mother-to-child transmission of HIV in Benin City, Edo State, Nigeria in conformity with the national guidelines.

Methodology: The study design was a descriptive cross-sectional survey. Health workers providing services for preventing mother-to-child transmission of HIV in Benin City, Edo State were recruited from seven health facilities. Data was collected using self-administered questionnaires between July 2011 and October 2011.

Results: The respondents comprised 270 health 88 males (32.6%) and 182 females (67.4%). 41.5% of health workers reported good practice of preventing mother-to-child transmission of HIV. The respondents identified several challenges of preventing mother-to-child transmission of HIV including heavy work load, irregular supply of HIV test kits and insufficient male involvement in preventing mother-to-child transmission of HIV.

Conclusion: The proportion of health workers with good, fair and poor practice of preventing mother-to-child transmission of HIV was 41.5%, 45.9% and 12.6%. The health workers identified several challenges during the course of the study. Addressing these challenges is crucial to achieving the goal of reducing mother-to-child transmission of HIV.